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Synthesis of peptides containing methylated Lysine residues


  Post-translational methylation of histone lysine residues is emerging as an important control mechanism for the regulation of protein expression, X chromosome activation, genomic imprinting and DNA repair. We successfully synthesised Fmoc-Lys(Me,Boc-OH, Fmoc-Lys(Me)2-OH and Fmoc-Lys(Me)3-OH and  implied into Solid phase peptide synthesis.

Our product:

No.

Peptide Sequence

1

ARTK(Me)QTARKS

2

ARTKQTARK(Me)2STGGKA

3

ARTK(Me)3QTARKSTGGGKAPKQLATKARK(Me)3SAPATGGVK

4

ARTK(Me)2QTARSTGGKARGAARK(Me)3SAPAGGVKK

  •   after months’ research, we have developed helical peptide. The building blocks of helical peptide are 2 amino acides modified with pentenyls, butenyls or allyls in the sequence... (2011.3.25)
  •  with the rapid increase of sales amount, the current production capacity could not satisfy our customer’s needs...(2011.3.20)
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